Omnibus Autism Proceeding

Omnibus Autism Proceeding

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HepB vaccine injury case

JANE DOE/23, Petitioner, v. SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, Respondent

 Office of Special Masters – U.S. Court of Federal Claims – “Each expert in the instant case agrees that optic neuritis is frequently a hallmark for MS. There is a logical sequence of cause and effect connecting petitioner’s exposure to hepatitis B vaccine and her onset of demyelinating disease. Petitioner has proved causation in fact.”

Invasive, paediatric, vaccine strains of Streptococcus pneumoniae: Are there differences in clinical characteristics?

Invasive, paediatric, vaccine strains of Streptococcus pneumoniae: Are there differences in clinical characteristics?

Abstract

Invasive pneumococcal infections in 777 adults caused by ‘invasive’ (1, 7; n=187), ‘paediatric’ (6, 9, 14, 19, 23; n=304) and other (n=286) serogroups were compared. Infections caused by ‘invasive’ strains caused pneumonia more often than other serogroups and were more often isolated from younger patients without concomitant conditions and had lower case-fatality rate than ‘paediatric’ and other strains. The 2 latter groups differed little from each other. Infections caused by strains in the 7-valent pneumococcal conjugate vaccine differed little from infections caused by non-vaccine types indicating that widespread use of this vaccine will not markedly change the clinical characteristics of invasive pneumococcal infections in adults.

Hepatitis B triple series vaccine and developmental disability in US children aged 1–9 years

Hepatitis B triple series vaccine and developmental disability in US children aged 1–9 years

 

Abstract

This study investigated the association between vaccination with the Hepatitis B triple series vaccine prior to 2000 and developmental disability in children aged 1-9 years (n = 1824), proxied by parental report that their child receives early intervention or special education services (EIS). National Health and Nutrition Examination Survey 1999-2000 data were analyzed and adjusted for survey design by Taylor Linearization using SAS version 9.1 software, with SAS callable SUDAAN version 9.0.1. The odds of receiving EIS were approximately nine times as great for vaccinated boys (n = 46) as for unvaccinated boys (n = 7), after adjustment for confounders. This study found statistically significant evidence to suggest that boys in United States who were vaccinated with the triple series Hepatitis B vaccine, during the time period in which vaccines were manufactured with thimerosal, were more susceptible to developmental disability than were unvaccinated boys.